MANUAL ARTICLE REVIEW IS REQUIRED FOR THIS ARTICLE

Manual article review is required for this article

16 AMP binding to Site 1 seems to induce allosteric activation, While binding of AMP or ADP to Web site 3 seems to modulate the phosphorylation condition of Thr172.thirteen Even though cellular ADP concentrations are bigger than All those of AMP, a new analyze has revealed that AMP can be a bona fide activator that enhances LKB1-dependent Thr 172 p